MND Australia

Daniel McLoone Major Research Initiative (2023–26)

The Daniel McLoone Major Research Initiative (MRI) aims to support an outstanding innovative and collaborative project that has the capacity to make a significant impact on Australian MND research.

The grant will be for up to a total of $1M for a 4-year project. The proposal must include a salary for an early-career researcher (ECR) who will play a major role in driving the outcomes of the research. If an exceptionally strong case is made, salary support for a key researcher who is pivotal to the outcomes of the project can be requested in place of the ECR salary.

The Daniel McLoone Major Research Initiative has been made possible by an incredibly generous bequest by Daniel McLoone’s family from his estate following his death.  

The research proposal must address one of the following areas:

  • Research that improves knowledge of the underlying disease mechanisms causing MND and the development of representative laboratory models.
  • Research that aims to lead to new treatments (excluding conducting clinical trials). Although the project may support research that could eventually lead to a clinical trial the Major Research Initiative cannot be used to directly support a clinical trial.
  • Clinical and healthcare research to promote innovation and best practice to improve quality of life for people living with MND and their families and carers.

The proposed project should support collaboration across the Australian MND research community, it is a requirement that significant contributions are made by researchers outside of the host institution.

The application should include an ECR fellow who will play a major role in producing the outcomes for the project. If an exceptionally strong case is made, salary support for a key individual who is pivotal to the outcomes of the project can be requested in place of the ECR salary.

The project should be a new initiative. If support is requested for an existing initiative, the funding should expand the original initiative to achieve novel outcomes beyond the scope of the original project. These additional benefits should be clearly defined and justified and the benefit to those living with MND described.

To reflect the broad reach of this funding initiative and the requirement for an integrated project, all grant categories will be weighted equally;

  • Research Quality - 25%
  • Innovation and creativity - 25%
  • Significance - 25%
  • Capability - 25%

Applications have now closed.

Application guidelines (updated 04/08/2022).